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  3. Article of Associate Professor Hashimoto (Faculty of Science and Engineering) et al. Appears on Front Cover of ELECTROPHORESIS for Third Consecutive Year

Article of Associate Professor Hashimoto (Faculty of Science and Engineering) et al. Appears on Front Cover of ELECTROPHORESIS for Third Consecutive Year

Updated Jan. 18, 2019
The article of the research group of Associate Professor HASHIMOTO Masahiko (Faculty of Science and Engineering, the Department of Chemical Engineering and Materials Science) et al. was featured on the front cover of the journal ELECTROPHORESIS (Volume 40, Issue 2), published on January 17, 2019, which marks the third consecutive year after 2017 and 2018.

The article is about the assay successfully developed for specific identification of DNA methylation, characterized as the representative example of epigenetic modifications. Associate Professor Hashimoto et al. made it possible to detect DNA methylation more rapidly, more conveniently and more economically than by conventional methods, by utilizing the method of fluorescence resonance energy transfer. This research is expected to enable cancer tests targeting methylated DNA to be carried out at higher speed and at a lower cost than before.

Title of the Article:
‘Separation-free single-base extension assay with fluorescence resonance energy transfer for rapid and convenient determination of DNA methylation status at specific cytosine and guanine dinucleotide sites’

Lead Author of the Article
HASHIMOTO Masahiko
Associate Professor, the Department of Chemical Engineering and Materials Science, the Faculty of Science and Engineering

Co-author:
FUJITA Keisuke (Completed Master's Programs in 2017, Applied Chemistry, the Graduate School of Science and Engineering)
The article of the research group of Associate Professor HASHIMOTO Masahiko (Faculty of Science and Engineering, the Department of Chemical Engineering and Materials Science) et al. was featured on the front cover of the journal ELECTROPHORESIS (Volume 40, Issue 2), published on January 17, 2019, which marks the third consecutive year after 2017 and 2018.

The article is about the assay successfully developed for specific identification of DNA methylation, characterized as the representative example of epigenetic modifications. Associate Professor Hashimoto et al. made it possible to detect DNA methylation more rapidly, more conveniently and more economically than by conventional methods, by utilizing the method of fluorescence resonance energy transfer. This research is expected to enable cancer tests targeting methylated DNA to be carried out at higher speed and at a lower cost than before.

Title of the Article:
‘Separation-free single-base extension assay with fluorescence resonance energy transfer for rapid and convenient determination of DNA methylation status at specific cytosine and guanine dinucleotide sites’

Lead Author of the Article
HASHIMOTO Masahiko
Associate Professor, the Department of Chemical Engineering and Materials Science, the Faculty of Science and Engineering

Co-author:
FUJITA Keisuke (Completed Master's Programs in 2017, Applied Chemistry, the Graduate School of Science and Engineering)
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