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Graduate School of Science and Engineering
Applied Chemistry

Bioinorganic and Chemical Biology Laboratory

Website of the Laboratory 【In English&Japanese】

A chemical understanding of life processes to develop bio-inspired molecules for industrial and medical uses

Staff

kodera

Masahito KODERA
[Professor]
Acceptable course
Master's degree course
Doctoral degree course
Telephone : +81-774-65-6652
mkodera@mail.doshisha.ac.jp
Office : SC-323
Database of Researchers
No Image

Yutaka HITOMI
[Professor]
Acceptable course
Master's degree course
Doctoral degree course
Telephone : +81-774-65-7437
yhitomi@mail.doshisha.ac.jp
Office : SC-308
Database of Researchers

Research Topics

  • Development of mono-, di-, and multinuclear metal complexes as bio-inspired efficient catalysts
  • Development of mono-, di-, and multinuclear metal complexes that can be used for chemical biology
  • Development of enzyme functional model complexes that function in water
  • Development of oxidative-stress-sensing probes
  • Development of bio-compatible multifunctional nanoparticles

Research Contents

We aim to deepen a chemical understanding of life processes through the synthesis of artificial molecules that can mimic the well-designed reactions that take place in living organisms, and based on this knowledge, we work on the development of functional molecules (catalysts, sensors, etc.) of use to humankind. This approach may be called biomimetics or bio-inspired, and it is expected to become a more and more important approach.
We are dedicated to developing a group of useful substances by focusing specifically on biological reactions involving metal ions, synthesizing artificial molecules that can mimic these in vivo reactions in order to understand life processes in the molecular level. We are also trying to introduce artificial molecules (designed based on an understanding of in vivo reactions) into living cells to examine the chemical reactions within living organisms.

Keywords

  • Dioxygen complex
  • Oxidation reaction
  • Enzyme functional model complex
  • Bio-inspired metal complex
  • Reactive oxygen species
  • Oxidative stress
  • Homeostasis
  • Fluorescent probes
  • Bio-imaging
  • Chemical biology
  • Bioinorganic chemistry